Actual Misfits: Andrew, Genova, Big Richard, Brad, Lenny, Jay
High ranking side characters (provided the most ments, were in the most videos, did podcasts, had big overall impact):
Collura, Emma, Dale, Adam Harper, Nate, Synthol Mark
Then you could go into mid-tier side characters who were present but not really too menty like: Saul, Will, Chuck the cat abandoner, coath Andrew, Todd, most of the other coaths, Cerebral palsy Mike
Low tier side characters: Hamberg, Macleod, Pomps, Cuban
??? tier characters (had lasting impact but highly disputed): Bessie Maybrook, Jane, Cynthia, Ian McCarthy, PJ Braun, Gideon, Lou, Robzilla
There are too many side characters to complete the list, for most it just turns into a 'who do I like' list. I'm not a misfits historian, but I've watched since about 2013. The actual misfits and the high ranking side characters are what the focus is on. Robzilla might be considered low tier by many based on how he's disliked, but in terms of ments provided he might be a high tier.